AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |
Back to Blog
Beginning of asepsis year11/19/2023 ![]() Globally, sepsis is common, with an estimated population incidence of 270 (95 % CI 176–412) cases per-100,000 person-years and acute mortality of 26.0 %. ![]() Sepsis has been redefined recently as life-threatening organ dysfunction caused by dysregulated host responses to infection and septic shock as a subset of sepsis in which particularly profound circulatory, cellular and metabolic abnormalities are associated with a greater risk of mortality than with sepsis alone. This review highlights the recent advances, clinical and methodological challenges in our understanding of these morbid events in sepsis survivors. For optimal design of interventional trials to reduce these bad outcomes in sepsis survivors, in-depth understanding of major risk factors for these morbid events, their modifiability and a causal relationship to the pathobiology of sepsis is essential. Sepsis survivors also have a higher risk of cognitive impairment and cardiovascular disease contributing to the reduced life expectancy seen in this population, when assessed with life table comparisons. In the first year following index sepsis episode, approximately 60 % of sepsis survivors have at least one rehospitalisation episode, which is most often due to infection and one in six sepsis survivors die. ![]() These sepsis survivors suffer from additional morbidities such as higher risk of readmissions, cardiovascular disease, cognitive impairment and of death, for years following index sepsis episode. Incidence of sepsis is increasing and the short-term mortality is improving, generating more sepsis survivors. Sepsis is life-threating organ dysfunction due to infection. ![]()
0 Comments
Read More
Leave a Reply. |